Research shows that acupuncture combined with medication improves endocrine hormone levels and ovari

This research has studied the clinical effect of acupuncture plus medication in the treatment of poor ovarian response (POR) patients.

A total of 100 volunteer POR women undergoing in vitro fertilization-embryo transplantation (IVF-ET) were recruited and were randomly divided into control, medication (Climen, composed of estradiol valerate and cyproterone acetate), acupuncture and acupuncture+medication (combined treatment) groups. Patients of the medication group were asked to orally take Climen (1 tablet/d for 21 days) beginning from the 3rd day of the menstruation, which was repeated for 3 menstrual cycles. Patients of the acupuncture group received manual acupuncture stimulation of Guanyuan (CV4), and bilateral Taixi (KI3), Sanyinjiao (SP6) of and Tai-chong (LR3) from day 8 to 15 of menstruation (follicular phase), once daily for 3 menstrual cycles. On the 2nd day of menstruation of the cycle, the ovarian reserve function was detected, including measurement of serum follicle-stimulating hormone (FSH), luteinizing hormone (LH), and estradiol (E2) contents. At the end of ovulation induction, the assisted pregnancy indexes and outcomes were studied, including administration of dosage and days of gonadotropin (Gn), the diameter of dominant oocyte, level of E2 on the trigger day, the numbers of ultrasound-guided-retrieved oocyte and the cultivated high-quality embryo (grade 1 and 2).

Their result has shown that

After the treatment, the contents of serum FSH, LH and E2 in the medication, acupuncture and combined treatment groups were significantly reduced and the content of serum AMH and ovary AFC in the medication, acupuncture and combined treatment groups were obviously increased in comparison with their own pre-treatment or with the control group. The group with medication plus acupuncture has the lowest levels of FSH, LH and E2. The dosage of Gn in the combined treatment group and the number of Gn administration days in the acupuncture and combined treatment groups were significantly fewer; serum E2 levels on the trigger day in the medication, acupuncture and combined treatment groups, and the high-quality embryo number in the combined treatment group were considerably higher. The high-quality embryo number in the combined treatment group was significantly larger.

References

Dong XLet al Zhen Ci Yan Jiu. 2019 Aug 25;44(8):599-604. doi: 10.13702/j.1000-0607.180779.

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